Hearing the words “unexplained infertility” can feel devastating. After months—or even years—of trying to conceive, it’s often the last thing you want to hear. But here’s the truth: unexplained infertility root causes often exist beneath the surface—they just haven’t been uncovered yet. This diagnosis doesn’t mean your body is broken or that your only option is IVF. It usually means things haven’t been looked at deeply enough yet. “Unexplained” really means not yet explained.
But here’s the truth: unexplained infertility usually just means not yet explained. That things haven’t been looked at deep enough yet – it doesn’t mean unsolvable. It means the standard tests haven’t found the issue—yet.
A Story of Hope: When Unexplained Infertility Wasn’t So Unexplained After All
Take my client Sarah (not her real name, of course). At 35, she and her partner had been trying for almost two years. She went through the standard fertility tests (you know, day 3 FSH, LH, TSH, Progesterone, and Estradiol)—everything came back “normal.” He did a standard semen analysis that was also “normal”. Her doctor told her she had unexplained infertility and to try IUI.
So Sarah and I started looking deeper. Together we uncovered four important clues: her progesterone was dropping too early in her cycle, she was severely deficient in vitamin D and iron, her inflammatory markers were super high and his “normal” semen analysis was suboptimal. Yes, his numbers fell within normal ranges, but they were on the low end (especially his motility). Unfortunately, these issues were subtle enough to be missed in the usual workup, but they were affecting her hormone balance and egg quality. And, his low motility was impacting how well his sperm was moving (a critical issue if it needs to meet up and fertilize an egg).
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Our plan included supporting her nutritional deficiencies with proper nutrition, gut support (ie. working on absorption — see ya later bloating), and thanks to this we saw a drop in her inflammatory markers. For him — high doses of antioxidants, omegas, and 8 hours of sleep vs the 5 1/2 he was used to. Once addressed—with targeted nutrition, supplements, and lifestyle shifts—her cycles were regulated, her luteal phase lengthened, his motility drastically improved and within six months she was pregnant.
Her story is proof that “unexplained” doesn’t mean unsolvable. It just means the real cause hasn’t been discovered yet.
So, next time you see your doctor, let’s make the most of your appointment.
Questions to Ask Your Doctor About Unexplained Infertility Root Causes
If you’ve been told your infertility is unexplained, consider asking:
- Could we look more closely at thyroid function beyond just TSH (ie. free T3, free T4, antibodies)?
- Has my uterine lining been evaluated for receptivity or chronic inflammation?
- Can we explore immune system or clotting factors that may affect implantation?
- Could my gut health or inflammation be influencing hormone balance?
- What are my vitamin D, B12, iron, and homocysteine levels?
- Have we assessed sperm DNA fragmentation, not just count and motility?
- Could insulin resistance or blood sugar issues be playing a role?
- Have we considered endometriosis—even if I don’t have pain?
The Takeaway: Unexplained Doesn’t Mean Unsolvable
“Unexplained” is not the end of your story. It’s an invitation to dig deeper, uncover the missing pieces, and take back your hope.
👉 If you’re ready to explore possible root causes behind your fertility struggles, let’s connect –>
Book a free Fertility Discovery Call here by filling out this quick form, and we’ll map out where you are, what may be missing, and how to move forward.
You’re NOT broken—you just need the right answers.
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